eta name="keywords" content="皮肤科,手术两百年,皮肤病,白血病,痛经,怀孕,荨麻疹">
氨甲环酸在皮肤科的4种用处，一文盘点
*仅供医学专业人士阅读参考
氨甲环酸可不止能祛斑，带你了解它在皮肤科的更多用法！
（图源锐景）
氨甲环酸是一种长期存在的抗纤维蛋白溶解剂，在皮肤病学中具有多种用途。 口服和皮内注射氨甲环酸已用于治疗黄褐斑。 口服氨甲环酸可预防遗传性血管性水肿发作。 氨甲环酸的不良反应包括腹痛、腹胀、恶心和呕吐、麻木或面部瘙痒、耳鸣、短暂性遗忘、震颤、痛经、脱毛、面部多毛症、唇部或眶周肿胀以及心悸。 应告知患者血栓栓塞事件的罕见风险，并在开始治疗前确定潜在的危险因素。
[1]LEE H C, THNG T G S, GOH C L. Oral tranexamic acid (TAAE) in the treatment of melasma: A retrospective analysis.[J]. Journal of the American Academy of Dermatology, 2016,75(2): 385-392.
[2]SHARMA R, MAHAJAN V K, MEHTAAE K S, et al. Therapeutic efficacy and safety of oral tranexamic acid and that of tranexamic acid local infiltration with microinjections in patients with melasma: a comparative study.[Z]. 2017: 42, 728-734.
[3]KHURANA V K, MISRI R R, AGARWAL S, et al. A randomized, open-label, comparative study of oral tranexamic acid and tranexamic acid microinjections in patients with melasma.[Z]. 2019: 85, 39-43.
[4]ATEFI N, DALVAND B, GHASSEMI M, et al. Therapeutic Effects of Topical Tranexamic Acid in Comparison with Hydroquinone in Treatment of Women with Melasma.[J]. Dermatology and therapy, 2017,7(3): 417-424.
[5]RUTNIN S, PRUETTIVORAWONGSE D, THADANIPON K, et al. A Prospective Randomized Controlled Study of Oral Tranexamic Acid for the Prevention of Postinflammatory HyperpigmentaAEtion After Q-Switched 532-nm Nd:YAG Laser for Solar Lentigines.[J]. Lasers in surgery and medicine, 2019,51(10): 850-858.
[6]BEAUCHÊNE C, MARTINS-HÉRICHER J, DENIS D, et al. [Tranexamic acid as first-line emergency treatment for episodes of bradykinin-mediated angioedema induced by ACE inhibitors].[J]. La Revue de medecine interne, 2018,39(10): 772-776.
[7]WINTENBERGER C, BOCCON-GIBOD I, LAUNAY D, et al. Tranexamic acid as maintenance treatment for non-histaAEminergic angioedema: analysis of efficacy and safety in 37 patients.[J]. Clinical and experimentaAEl immunology, 2014,178(1): 112-117.
[8]ZILINSKY I, BARAZANI T B, SHENKMAN B, et al. Topical HemostaAEtic-Anesthetic Solution to Reduce Bleeding During Mohs Micrographic Surgery: A Case Control Study.[J]. Journal of drugs in dermatology : JDD, 2016,15(7): 851-855.
[9]KWON H J, SUH J H, KO E J, et al. Combination treatment of propranolol, minocycline, and tranexamic acid for effective control of rosacea.[Z]. 2017: 30.
[10]KIM S J, PARK J, SHIBATAAE T, et al. Efficacy and possible mechanisms of topical tranexamic acid in melasma.[J]. Clinical and experimentaAEl dermatology, 2016,41(5): 480-485.
[11]HOFMAN Z, de MAAT S, HACK C E, et al. Bradykinin: Inflammatory Product of the Coagulation System.[J]. Clinical reviews in allergy & immunology, 2016,51(2): 152-161.
本文来源：医学界皮肤频道
本文作者：繁星
本文审核：唐教清
责任编辑：香菜
欢迎来稿分享！
